Pharmaceutical Residue Testing
Pharmaceutical Residue Analysis “P- and U- Listed” Hazardous Waste
Unused pharmaceutical commercial chemical products (CCPs) or manufacturing chemical intermediates often contain harmful wastes when improperly discarded. According to the U.S. Environmental Protection Agency (EPA) all P- and U- listed wastes (hazardous and toxic respectively) are subject to proper disposal protocol regulated by the EPA.
Although empty or unused objects such as pill bottles, inner liners of containers, wrappers, wipes and even paper cups used to deliver pharmaceuticals to patients typically have small amounts of chemical waste that cannot be visibly detected, such items often contain hazardous or toxic residues. If not triple rinsed with the proper solvent, cleaned by an alternative method or removed of its inner liner, the container is not considered empty by the Resource Conservation and Recovery Act (RCRA) even if P- and U- listed pharmaceuticals were fully dispensed.
P-listed acute-hazardous wastes generated in quantities greater than 1 kg in one calendar month from non specific sources and/or discarded CCP, off specification species, container residues and spill residues are subject to full regulation (regulations applicable to hazardous generators of 1000 kg or greater) according to EPA. Any P-listed residue or contaminated soil, waste, or other debris from clean-up of spill into or on any land or water of any acute hazardous P-listed waste greater than 100 kg is also subject to EPA full regulation policy.
U-listed toxic wastes generated in quantities less than or equal to 100 kg in one calendar month by a conditionally exempt small quantity generator must comply with specific EPA requirements to be excluded from full regulation. Warfarin and its salts with concentrations greater than 0.3 % are “P-listed” and subject to full regulation whereas those with concentrations = 0.3 % are “U-listed” and subject to small quantity generator exclusion regulated by the EPA.
Forensic Analytical Sciences provides the detailed analysis of pharmaceutical containers that have carried any commercial chemical product or manufacturing chemical intermediate. Submit your CCPs to our laboratory for analysis to confirm the weight and concentration of warfarin residue and other pharmaceuticals upon request. We use advanced instrumentation and analytical techniques to deliver accurate and reliable results, which could save you from undesirable penalties for the unsafe storage handling or improper disposal of hazardous wastes.